Clik here to view.
Modeling an Accurate Drug Delivery Device
There are many different routes through which drugs and other medications can be delivered into a patient’s body during treatment. These include topographical ointments, pills, vaporizers, and...
View ArticleClik here to view.
Modeling Electroosmotic Flow and the Electrical Double Layer
Microfluidic devices are so small that the micropumps and micromixers that control and mix the fluid inside the device cannot involve any moving components. Instead, they must take advantage of...
View ArticleClik here to view.
Thermometer Calibration: When Experimentation Falls Short
The International Temperature Scale of 1990 (ITS-90) is the industry calibration standard for measuring temperatures throughout the world. The National Physical Laboratory (NPL) works to establish and...
View ArticleClik here to view.
Red Blood Cell Separation from a Flow Channel
Before conducting certain blood sample analyses, researchers need to separate the red blood cell particles from the blood plasma. Using lab-on-a-chip (LOC) technology, red blood cell separation can be...
View ArticleClik here to view.
Buoyancy-Driven μPCR for DNA Amplification
DNA is a complex molecule that contains instructions for life and often referred to as a “digital fingerprint” or code telling a cell what to do. DNA is often the only means for accurate testing and...
View ArticleClik here to view.
Tesla Microvalve Model as a Topological Optimization Example
Topological optimization is routinely used in the design and refinement of microfluidics devices. The process also comes in handy for modeling a Tesla microvalve. What Is a Tesla Microvalve? The Tesla...
View ArticleClik here to view.
Dielectrophoretic Separation
How can you use an electric field to control the movement of electrically neutral particles? This may sound impossible, but in this blog entry, we will see that the phenomenon of dielectrophoresis...
View ArticleClik here to view.
Which Multiphase Flow Interface Should I Use?
If you are interested in using COMSOL Multiphysics software to solve multiphase flow problems, you may be wondering which multiphase flow interface to choose. This is your guide to the six interface...
View ArticleClik here to view.
Tears of Wine and the Marangoni Effect
Try pouring some wine into a glass. Don’t drink it yet — this is a scientific experiment. When you hold up your glass, you’ll see what look like teardrops running down the sides. These tears of wine...
View ArticleClik here to view.
Simulating Analog-to-Digital Microdroplet Dispensers for LOCs
Microfluidic biochips have a variety of applications and are valued for their low cost, fast response time, and high efficiency. In the paper “Design and Simulation of High-Throughput Microfluidic...
View ArticleClik here to view.
Simulating a Valveless Micropump Mechanism
Microfluidic systems often rely on valveless pumps, as they are both gentle on the biological material and low in the risk of clogging. However, by design, this type of pump is not suitable for viscous...
View ArticleClik here to view.
Creating Ultrafast Polymerase Chain Reaction Tests with LEDs
Polymerase chain reaction tests have many applications within medical and biological research. In the past, these tests have been performed within a laboratory setting due to their high power...
View ArticleClik here to view.
Focusing on an Electrowetting Lens
Adjusting the focal length of a camera lens allows you to change your angle of view. Miniature lenses can achieve this change by using a method called electrowetting. Electrowetting involves changing...
View ArticleClik here to view.
Simulate Three-Phase Flow with a New Phase Field Interface
In COMSOL Multiphysics version 5.2, the CFD and Microfluidics modules include a new fluid flow interface for modeling separated three-phase flow. The model behind this fluid flow interface accounts for...
View ArticleClik here to view.
Model How the Bubbles in a Glass of Stout Beer Sink, Not Rise
When you think of a stout beer, one type that may come to mind is Guinness® beer. This stout is very special, noticeable by its dark body and famous white head. The dynamics of the foam alone are...
View ArticleClik here to view.
Evaluating an Insulin Micropump Design for Treating Diabetes
In any form of treatment, it is always desirable to minimize the level of discomfort that the treatment process causes patients, while ensuring overall safety and effectiveness. For diabetes patients,...
View ArticleClik here to view.
Designing Effective Transdermal Drug Delivery Patches with Simulation
Transdermal drug delivery (TDD) patches continuously deliver drugs into the body for a certain amount of time. However, the skin is designed to keep out foreign substances, like drugs. To create a TDD...
View ArticleClik here to view.
Designing Inkjet Printheads for Precise Material Deposition
If an inkjet printhead nozzle is poorly designed, it will lead to a low-quality end product — whether it’s used in a 2D or 3D printer, the fabrication of an integrated circuit, or even DNA synthesis....
View ArticleClik here to view.
Keynote Video: Solving 2 Transport Process Problems with Simulation
For those looking to solve complex transport process problems involving photonics and microfluidics, it can be challenging to account for all of the elements involved, including multiple physics...
View ArticleClik here to view.
Preventing Bubble Entrapment in Microfluidic Devices Using Simulation
If bubbles in a microfluidic device become stuck, it can cause the device to malfunction. Bubble entrapment depends on several factors, including the geometry and flow characteristics of the...
View Article